Hotels > Texas > Houston > Hotels near South Main Street Use this guide to find hotels and motels near South Main Street in Houston, Texas. | | 1. Staybridge Suites Medical Center Houston 9000 South Main Street, Houston, TX 77025 Call Us 0.1 mile from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated High
- Upscale, smoke-free, all-suite, extended-stay hotel
- Near NRG Stadium
- 5 floors, 120 studio to 2-bedroom suites
- Outdoor swimming pool - 24-hour exercise room
- Kitchen in every suite
- Free hot breakfast buffet
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 35 reviews Read Recent Reviews | |
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9300 South Main Street, Houston, TX 77025 Call Us 0.2 mile from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Very High
- Upper-midscale, smoke-free hotel near NRG Park and Stadium
- 4 floors, 146 rooms and suites
- Free shuttle to Houston Medical Center
- Outdoor swimming pool - 24-hour exercise room
- Microwave and refrigerator in every room
- Free hot breakfast buffet
- Free WiFi
- Free parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 116 reviews Read Recent Reviews | More Reviews |
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3. Hotel Ylem Houston 8080 South Main Street, Houston, TX 77025 Call Us 0.6 mile from South Main Street Houston
| EnterDates | Check In | 1500 | Check Out | 1200 |
| Rated Average
- Upper-midscale, smoke-free hotel
- Near NRG Park and Stadium
- 3 floors, 79 rooms and suites - elevator
- No swimming pool
- Exercise room
- Microwave and refrigerator in every room
- Free hot breakfast buffet
- Free WiFi
- Free parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 215 reviews Read Recent Reviews | More Reviews |
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4. Wingate by Wyndham Hotel NRG Park Medical Center Houston 8600 Kirby Drive, Building B, Houston, TX 77054 Call Us 0.6 mile from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated Very Low Not Recommended
- Midscale, smoke-free hotel
- 2 miles from NRG Stadium
- 4 floors, 259 rooms
- Outdoor swimming pool open in summer Exercise room
- Free continental breakfast
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 3 reviews Read Recent Reviews | |
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5. Holiday Inn South Loop Houston 8111 Kirby Drive at LaConcha, Houston, TX 77054 Call Us 0.6 mile from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Average
- Upper-midscale, smoke-free hotel
- 2 blocks from NRG Park and Stadium
- 11 floors, 238 rooms and suites
- Free shuttle to local attractions
- Outdoor swimming pool open all year - exercise room
- Restaurant - lounge - room service
- Restaurant open for breakfast and dinner only
- Free WiFi
- Parking costs $7 per night - truck parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 395 reviews Read Recent Reviews | More Reviews |
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6. Americas Best Value Inn NRG Park Houston 7905 South Main St and Old Spanish Trail, Houston, TX 77025 Call Us 0.6 mile from South Main Street Houston
| EnterDates | Check In | 13 00 | Check Out | 12 00 |
| Rated Average
- Cheap motel
- 3 blocks north of NRG Park and Stadium
- 2 floors, 73 rooms - elevator
- Some smoking rooms
- No swimming pool
- Microwave and refrigerator in every room
- Free continental breakfast
- Free WiFi
- Free parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 58 reviews Read Recent Reviews | More Reviews |
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7. Extended Stay America Suites La Concha Houston 1303 La Concha Lane, Houston, TX 77054 Call Us 0.7 mile from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated Average
- Budget, smoke-free, all-suite, extended-stay hotel
- Near NRG Park and Houston Medical Center
- 3 floors, 85 studio suites - elevator
- Free shuttle to Texas Medical Center
- Outdoor swimming pool open in summer Exercise room
- Kitchen in every suite
- Free continental breakfast
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 145 reviews Read Recent Reviews | More Reviews |
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8. Wyndham Hotel near NRG Park and Medical Center Houston 8686 Kirby Drive at I-610 South, Houston, TX 77054 Call Us 0.7 mile from South Main Street Houston
| EnterDates | Check In | 1500 | Check Out | 1100 |
| Rated Average
- Upscale, smoke-free, full-service hotel
- Across the street from NRG Park
- 8 floors, 652 rooms and suites
- Outdoor swimming pool open in summer Exercise room
- Restaurant - lounge - room service
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 545 reviews Read Recent Reviews | More Reviews |
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9. Residence Inn by Marriott Medical Center Houston 7807 Kirby Drive, Houston, TX 77030 Call Us 0.7 mile from South Main Street Houston
| EnterDates | Check In | 1600 | Check Out | 1100 |
| Rated Very High
- Upscale, smoke-free, all-suite, extended-stay hotel
- Near NRG Stadium
- 16 floors, 182 studio, 1-bedroom, and 2-bedroom suites
- Heated indoor swimming pool - exercise room
- Restaurant - lounge
- Restaurant open for dinner only
- Kitchen in every suite
- Free hot breakfast buffet
- Free WiFi
- Parking costs $7 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 45 reviews Read Recent Reviews | More Reviews |
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10. Candlewood Suites Medical Center Houston 10025 Main Street, Houston, TX 77025 Call Us 0.8 mile from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Average
- Midscale, smoke-free, all-suite, extended-stay hotel
- Near NRG Park
- 4 floors, 80 suites
- Free shuttle within a 5-mile radius
- Indoor swimming pool - 24-hour exercise room
- Kitchen in every suite
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 103 reviews Read Recent Reviews | More Reviews |
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1715 Old Spanish Trail, Houston, TX 77054 Call Us 1.3 miles from South Main Street Houston
| EnterDates | Check In | 16 00 | Check Out | 11 00 |
| Rated High
- Upper-midscale, smoke-free hotel 1 mile north of NRG Park
- 1 mile west of VA Hospital - 2 blocks from metrorail station
- Free shuttle to attractions within 3-mile radius
- 5 floors, 120 rooms and suites
- Outdoor swimming pool - exercise room
- Free continental breakfast
- Free WiFi
- Parking costs $6 per night
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 955 reviews Read Recent Reviews | More Reviews |
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12. Hyatt Place Hotel Medical Center Houston 7329 Fannin Street, Houston, TX 77030 Call Us 1.4 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| - Upscale, smoke-free hotel
- Located near Texas Medical Center Campus
- Also near NRG Stadium and Houston Zoo
- 13 floors, 157 rooms
- Free shuttle to local attractions within 2-mile radius
- Outdoor swimming pool - exercise room
- Restaurant - lounge
- Restaurant open for dinner only
- Free hot breakfast buffet
- Pet friendly hotelMore >
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13. Hyatt House Hotel Medical Center Houston 7329 Fannin Street, Houston, TX 77030 Call Us 1.4 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated High
- Upscale, smoke-free, extended-stay hotel
- Located near Texas Medical Center Campus
- Also near NRG Stadium and Houston Zoo
- 13 floors, 141 rooms and suites
- Free shuttle to local attractions within 2-mile radius
- Outdoor swimming pool - exercise room
- Restaurant - lounge
- Restaurant open for dinner only
- Free continental breakfast
- Pet friendly hotelMore >
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14. Blossom Hotel Medical Center Houston 7118 Bertner Avenue, Houston, TX 77030 Call Us 1.6 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Very High
- Upscale, smoke-free, full-service hotel
- 3 miles from NRG Stadium
- 16 floors, 267 rooms and suites
- Outdoor rooftop swimming pool - exercise room
- Restaurant - lounge - room service
- Free WiFi
- Valet parking only - $35 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 225 reviews Read Recent Reviews | |
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6800 Main Street, Houston, TX 77030 Call Us 1.8 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated High
- Upscale, smoke-free hotel
- Near Houston Medical Center and Rice University
- Easy access to MD Anderson Cancer Center
- Also near METRORail
- 12 floors, 287 rooms and suites
- Outdoor swimming pool open in summer
- Exercise room
- Restaurant - lounge
- Restaurant open for breakfast and dinner only
- Free WiFi
- Parking costs $15 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 1349 reviews Read Recent Reviews | More Reviews |
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16. InterContinental Hotel Medical Center Houston 6750 Main Street, Houston, TX 77030 Call Us 1.8 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Very High
- Luxury, smoke-free, full-service hotel by Texas Medical Center
- 21 floors, 354 rooms and suites
- Heated outdoor swimming pool open in summer
- 24-hour exercise room
- Restaurant
- Restaurant open for breakfast and dinner only
- Free WiFi
- Parking costs $22 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 280 reviews Read Recent Reviews | More Reviews |
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17. Surestay Plus Hotel by Best Western Houston Medical Center 6700 Main Street, Houston, TX 77030 Call Us 1.9 miles from South Main Street Houston
| EnterDates | Check In | 1500 | Check Out | 1200 |
| Rated Average
- Midscale, smoke-free hotel near Houston Methodist Hospital
- Also near Rice University and Texas Medical Center
- 1 mile from zoo
- 6 floors; 125 rooms, 25 suites
- Free shuttle to local attractions
- Heated indoor swimming pool - exercise room
- Microwave and refrigerator in every room
- Free hot breakfast buffet
- Free WiFi
- Free parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 864 reviews Read Recent Reviews | More Reviews |
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18. Hilton Plaza Hotel Texas Medical Center Houston 6633 Travis Street, Houston, TX 77030 Call Us 2.0 miles from South Main Street Houston
| EnterDates | Check In | 16 00 | Check Out | 11 00 |
| Rated Average
- Upper-upscale, smoke-free, full-service hotel
- Near Houston Medical Center
- Also near Rice University and Zoo
- Free shuttle to attractions within 2-mile radius
- Outdoor swimming pool open in summer Exercise room
- Restaurant - lounge
- Free WiFi
- Parking costs $15 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 100 reviews Read Recent Reviews | More Reviews |
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19. Westin Hotel Medical Center Houston 1709 Dryden Road, Houston, TX 77030 Call Us 2.0 miles from South Main Street Houston
| EnterDates | Check In | 1500 | Check Out | 1200 |
| Rated Very High
- Upscale, smoke-free, full-service hotel
- Near Texas Medical Center
- 18 floors, 273 rooms and suites
- Free shuttle to attractions within 3-mile radius
- Outdoor swimming pool open in summer Exercise room
- Restaurant - lounge - room service - coffee shop
- Free WiFi
- Valet parking only - $35 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 396 reviews Read Recent Reviews | More Reviews |
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20. Marriott Hotel at Texas Medical Center Houston 6580 Fannin Street, Houston, TX 77030 Call Us 2.1 miles from South Main Street Houston
| EnterDates | Check In | 1600 | Check Out | 1200 |
| Rated Very High
- Upper-upscale, smoke-free, full-service hotel
- Near Houston Medical Center and Rice University
- Skyway to medical schools and Methodist Hospital
- Skyway to Scurlock and Smith Towers
- Free shuttle to attractions within 2-mile radius
- Heated indoor swimming pool - exercise room
- 2 restaurants - lounge - room service
- Free WiFi
- Valet parking only - $28 per night
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 1140 reviews Read Recent Reviews | More Reviews |
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21. Locale Apartments Medical Center Houston 1911 Holcombe Blvd, Houston, TX 77030 Call Us 2.2 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated Very High
- Upscale, smoke-free, midtown, furnished apartments
- Near Houston Medical Center
- 22 floors, 21 1-bedroom and 2-bedroom apartments
- Outdoor swimming pool open all year - exercise room
- Kitchen in every apartment
- Free WiFi
- Parking costs $20 per night
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 4 reviews Read Recent Reviews | |
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22. Home2 Suites by Hilton Medical Center Houston 6840 Almeda Road, Houston, TX 77030 Call Us 2.4 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Very High
- Upper-midscale, smoke-free, extended-stay hotel
- 2 miles from Texas Medical Center
- 10 floors, 143 studio and 1-bedroom suites
- Outdoor swimming pool open all year - exercise room
- Kitchen in every suite
- Free hot breakfast buffet
- Free WiFi
- Parking costs $15 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 22 reviews Read Recent Reviews | |
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23. Hilton Garden Inn Medical Center Houston 6840 Almeda Road, Houston, TX 77030 Call Us 2.5 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Very High
- Upscale, smoke-free hotel
- 2 miles from Texas Medical Center
- 10 floors, 157 rooms and suites
- Outdoor swimming pool open all year - exercise room
- Restaurant - lounge
- Restaurant open for breakfast and dinner only
- Microwave and refrigerator in every room
- Free WiFi
- Parking costs $15 per night
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 19 reviews Read Recent Reviews | More Reviews |
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24. MainStay Suites Medical Center Houston 3134 Old Spanish Trail, Houston, TX 77054 Call Us 2.7 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated Average
- Midscale, smoke-free, all-suite, extended-stay hotel
- Near NRG Park and NRG Stadium
- 4 floors, 93 suites
- Free shuttle to Houston Medical Center
- Free shuttle to other attractions within 3-mile radius
- Heated outdoor swimming pool - exercise room
- Kitchen in every suite
- Free hot breakfast buffet
- Free WiFi
- Free parking - truck parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 374 reviews Read Recent Reviews | More Reviews |
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25. Courtyard by Marriott Hotel West University Houston 2929 Westpark Drive, Houston, TX 77005 Call Us 2.9 miles from South Main Street Houston
| EnterDates | Check In | 1500 | Check Out | 1200 |
| Rated High
- Upscale, smoke-free hotel
- 2 miles northwest of Rice University
- 3 floors, 98 rooms and suites - elevator
- Outdoor swimming pool open all year - exercise room
- Lounge
- Free WiFi
- Free parking
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 211 reviews Read Recent Reviews | More Reviews |
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26. Residence Inn by Marriott West University Houston 2939 Westpark Drive, Houston, TX 77005 Call Us 2.9 miles from South Main Street Houston
| EnterDates | Check In | 1500 | Check Out | 1200 |
| Rated High
- Upscale, smoke-free, all-suite, extended-stay hotel
- 1 mile east of Greenway Plaza
- Free shuttle to attractions within 3-mile radius
- Outdoor swimming pool - 24-hour exercise room
- Microwave and refrigerator in every suite
- Free hot breakfast buffet
- Free WiFi
- Free parking - truck parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 194 reviews Read Recent Reviews | More Reviews |
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27. Crowne Plaza Hotel Med Center Houston 2712 SW Freeway, US 59, Houston, TX 77098 Call Us 3.1 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated High
- Upscale, smoke-free, full-service hotel
- 1 mile northwest of Rice University
- 9 floors, 243 rooms and suites
- Free shuttle to attractions within 3-mile radius
- Outdoor swimming pool - 24-hour exercise room
- Restaurant - lounge - room service
- Microwave and refrigerator in every room
- Free WiFi
- Parking costs $20 per night
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 1815 reviews Read Recent Reviews | More Reviews |
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28. Extended Stay America Suites Southwest Houston 2330 SW Freeway, US 59, Houston, TX 77098 Call Us 3.1 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 11 00 |
| Rated Average
- Budget, smoke-free, all-suite, extended-stay hotel
- 1 mile northwest of Rice University
- 3 floors, 122 suites - elevator
- No swimming pool
- Kitchen in every suite
- Free continental breakfast
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 195 reviews Read Recent Reviews | More Reviews |
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29. La Quinta Inn Greenway Plaza Houston 4015 SW Freeway, US 59, Houston, TX 77027 Call Us 3.2 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated Very Low Not Recommended
- Midscale, smoke-free hotel
- 5 miles northwest of Houston Medical Center
- Free shuttle to Houston Medical Center
- Outdoor swimming pool open in summer
- Microwave and refrigerator in every room
- Free continental breakfast
- Free WiFi
- Free parking
- Pet friendly hotelMore >
TripAdvisor Traveler Rating:
Based on 650 reviews Read Recent Reviews | More Reviews |
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30. DoubleTree by Hilton Hotel Greenway Plaza Houston 6 Greenway Plaza East, Houston, TX 77046 Call Us 3.2 miles from South Main Street Houston
| EnterDates | Check In | 15 00 | Check Out | 12 00 |
| Rated High
- Upscale, smoke-free, full-service hotel
- 5 miles southwest of downtown Houston
- Free shuttle to attractions within 3-mile radius
- Heated outdoor swimming pool - 24-hour exercise room
- Restaurant - lounge - room service - cafe
- Internet access costs $13 per night
- Parking costs $18 per night
- Not pet friendly
TripAdvisor Traveler Rating:
Based on 1395 reviews Read Recent Reviews | More Reviews |
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Hotels near NRG Stadium0.6 mile east Hotels near 2024 College Football Championship Game0.6 mile east Hotels near Jollibee0.6 mile NE Hotels near Houston Livestock Show and Rodeo0.7 mile east Hotels near Houston Astrodome0.8 mile east Hotels near Houston NRG Center0.9 mile east Hotels near NRG Arena1.0 mile east Hotels near Texas Orthopedic Hospital1.2 miles NE Hotels near Fannin Street Houston1.5 miles NE Hotels near Baylor Medicine McNair Campus1.8 miles NE Hotels near Texas Children's Hospital1.9 miles NE Hotels near Baylor St Luke's Medical Center1.9 miles NE Hotels near Old Spanish Trail2.0 miles NE Hotels near Kirby Drive Houston2.0 miles north Hotels near MD Anderson Cancer Center2.1 miles NE
We order the hotels on this page by how close they are to this attraction.Most of our competitors order these same hotels in other ways that make them more money.
To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.At hotels, on the other hand, you can enter your room only through a hall inside the building.
- Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas?
- Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot because some hotels' profit strategy is to get paid more than once for the same room for the same night.
- Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty?More >
- When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
- The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.
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